Effects of cadmium chloride on some links of energy metabolism in erythrocytes and bone marrow cells of white rats

H. L. Antonyak, Yu. V. Zhylishchych

The effects of cadmium cations on activity of energy metabolism enzymes in erythrocytes and erythroid bone marrow cells of white rats under prolonged intragastric introduction of CdCl2 in a dose of 3 mg/kg were studied. It was established that during the 21-daily trial period pyruvate kinase activity in animal erythrocytes increased, and in bone marrow cells - was inhibited, lactate dehydrogenase activity increased, and glucose-6-phosphate dehydrogenase was reduced in both types of cells studied. The results suggest the changes in erythroid cell energy metabolism under the influence of cadmium cations.

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