Comparison effect of selenium-containing yeasts Phaffia rhodozyma biomass and sodium selenite on some metabolisms characteristics of rats at oxidative stress

M. V. Kaminska, N. I. Boretska, H. I. Nechay, S. V. Hural, H. V. Kolisnyk

Comparative information about influence of selen-containing biomass of karotin- synthesizing yeasts Phaffia rhodozyma and sodium selenite on content of lipid peroxidation products, activity of antioxidant defense enzymes and aminotransferases in blood and liver of rats at oxidative stress modelled by tetra chloromethane is presented in this article.

A positive effect is set at the use of biomass of yeasts: decline of activity of alaninaminotransferazy in plasma of blood of rats on 47 % and aspartataminotransferazy on 9 %, umenshenie maintenances of dienovykh kon'yugatov in 3,6 time and TBK-active products in the liver of krysna 18 % as compared to the group of stress-control. At the use of selenite of sodium activity of ALAT in plasma of blood was increased on 51 %, however much maintenance of dienovykh kon'yugatov and TBK-active products went down in the liver of intoksicirovannykh rats. Introduction to the ration of intoksicirovannykh tetrakhlormetnom rats of biomassy of yeasts of P. rhodozyma with maintenance of selenium 2 the mcg/gramme of dry mass is shown by the best protective effect from the consequences of oxidative stress, what selenite of sodium.

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