Fish-based characterization of chromosomal rearrangement in the domestic pig

B. Danielak-Czech, U. Kaczor

The present study is an example of molecular approach in characterization of karyotype abnormalities in the domestic pig. Chromosome microdissection and chromosome painting techniques were applied for detailed diagnosis of reciprocal translocation in hypoprolific boar. Dual-colored FISH analysis of t(7;13)(13;q46) confirmed definitely previous identification based on high-resolution-RBA/GTG banding techniques. The experiment proved that such diagnostic refinements followed by early selection of animals carrying chromosomal rearrangements would efficiently prevent genetic defects from spreading in pig populations and limit economic effects.

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