Homocysteine level and changes of lipid metabolism in diabetes mellitus type 2 associated with coronary heart disease

H. O. Milovanova, B. O. Tsudzevych, Yu. I. Slyvchuk

In the development of type 2 diabetes the important part plays such a vascular pathology as diabetic angiopaty which appeared as a result of endothelial dysfunction. Despite the hyperhomocysteinemia is also present at vascular atherosclerosis. The article presents experimental data determination of homocysteine in the blood in diabetes mellitus type 2. Established that the conditions of prolonged hyperglycemia and content HbA1C> 7 % in the insulin-independent diabetes level of total homocysteine in plasma increases along with the progress of diabetic dyslipidemia.

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