Immunomodulation and anti inflammation effects of antibiotics

V. M. Zotsenko

The data about effects of different group antibiotics on interferon and tumor necrosis factor producing by mononuclear's bovine peripheral blood are presented in this article. It was established, that preparations which antimicrobial mechanism is caused by ability to suppress protein synthesis, has inhabiting abilities concerning cytokine-creation processes. The received modulating effects have dose-depended character. The highest anti-inflammatory abilities are revealed at macrolids and flouroquinolones, and lowest at beta-lactamm antibiotics.

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