EFFECTS OF CHROMIUM (VI) ON THE ACTIVITY OF ENZYMES OF ENERGY METABOLISM AND ANTIOXIDANT SYSTEM IN ANIMAL ERYTHROCYTES

H. L. Antonyak, O. B. Skab

The activities of enzymes of energy metabolism and antioxidant system in erythrocytes of rats, which were injected with potassium dichromate (K2Cr2O7) in dose 3mg/kg every day for 7 and 14 days, were investigated. It was established, that inhibition of lactate dehydrogenase, and glucose-6-phosphate dehydrogenase activities, as well as activation of antioxidant enzymes superoxide dismutase and glutathione peroxidase took place in animal red cells under an influence of Cr6+.

Download full text in PDF format