Changes of activity of enzymes-antioxidants in leucocytes of white rats after the long-term administration of cadmium chloride

H. L. Antonyak, L. P. Biletska

The effects of prolonged administration (during 14-day period) of cadmium chloride (3 mg/kg body weight) on intensity of enzymes of antioxidant system in leucocytes of white rats were studied. It was established, that under an influence of CdCl2 enzyme activities in lymphocytes and neutrophilic granulocytes of rats changed in different ways, namely: both the superoxide dismutase and glutathione peroxidase activities were increased, and catalase activity was diminished.

Download full text in PDF format