State of antioxidative system in rat's bone marrow cells during feeding with yeasts phaffia rhodozyma biomass.

M. I. Kolisnyk, V. V. Vlizlo

The influence of ?-carotene and carotenoproducing yeasts P. rhodozyma biomass on lipid peroxidation and antioxidative enzymes activity in rats' bone marrow was studied. It was established that the addition of yeast P. rhodozyma biomass decreases superoxide dismutase and catalase activity and diminishes accumulation of primary and secondary products of lipid peroxidation in bone marrow cells. Feeding with ?-carotene makes an ambiguous impact. Thus concentration of TBA-reactive substances decreases in white blood cells but level of diene conjugate and gluthathione peroxidase activity increases in red blood cells.

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