Correction of hypertonic cryohemolysis of human and bovine erythrocytes using anion amphiphilic compounds

N. M. Shpakova, N. A. Pisarenko, N. V. Orlova, V. N. Khmelkov

Studying of the efficiency of alkylsulphates with different length of alkyl chain under hypertonic cryohemolysis of human and bovine erythrocytes has shown higher anti-hemolytic activity of short-chain homologue sodium decylsulphate in comparison with long-chain sodium dodecylsulphate.

Both sodium decyl- and dodecylsulphates demonstrate more protective effect during hypertonic cryohemolysis of bovine erythrocytes.

Obtained research data testify to the fact that with a rise in salt concentration in incubation medium (though initial level of hypertonic cryohemolysis of bovine erythrocytes increases and for human cells it reduces), a decrease in efficiency of alkylsulphates for erythrocytes of both types is observed.

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